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Previous studies have shown that low socioeconomic status is associated with a first myocardial infarction, but these findings could not be extended to heart attack survivors to calculate their risk o ...


Mineralocorticoid receptor antagonists ( MRAs ) have been demonstrated to improve outcomes in reduced ejection fraction heart failure ( HFrEF ) patients. However, MRAs added to conventional treatmen ...


Guidelines strongly recommend patients with heart failure with reduced ejection fraction ( HFrEF ) be treated with multiple medications proven to improve clinical outcomes, as tolerated. The degree t ...


Beta-blockers are the cornerstone of therapy for heart failure; however, the effects of these drugs on the prognosis of patients with concomitant atrial fibrillation remain controversial. The obje ...


There are no studies of mineralocorticoid receptor antagonist ( MRA ) treatment examining outcome in unselected real-life patients with myocardial infarction and heart failure. There is uncertainty ...


A study has assessed the relationship between atrial fibrillation and outcomes in the TOPCAT ( Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist ) trial, to evaluat ...


Since the precise mechanism(s) of cognitive disorders in patients with atrial fibrillation ( AF ) is not fully known, the optimal way to prevent cognitive dysfunction for a given patient remains to be ...


Longitudinal studies have shown that dementia is more common in patients diagnosed with atrial fibrillation ( AF ) even in the absence of stroke. A meta-analysis of eight prospective studies evaluat ...


It is well established that atrial fibrillation increases the risk of clinical stroke by four- to five-fold, and patients with a clinical history of stroke are at increased risk of developing dementia ...


Evidence suggests that atrial fibrillation ( AF ) is associated with a higher risk for cognitive impairment and dementia, with or without a history of clinical stroke. Two meta-analyses that include ...


Current guidelines advocate the use of marine-derived Omega-3 fatty acids supplements for the prevention of coronary heart disease and major vascular events in people with prior coronary heart disease ...


Although silent myocardial infarction ( SMI ) accounts for about one-half of the total number of myocardial infarctions ( MIs ), the risk of heart failure ( HF ) among patients with silent myocardial ...


Elevated serum uric acid concentration ( SUA ) has been associated with an increased risk of cardiovascular disease, but this may be due to unmeasured confounders. Researchers have examined the as ...


Sacubitril / Valsartan ( Entresto ) has been shown to improve mortality and reduce hospitalizations in patients with heart failure with reduced ejection fraction ( HFrEF ). The effect of combination ...


The quality of evidence regarding patient-centered outcomes in adults with heart failure after Sacubitril combined with Valsartan ( Entresto ) has not been systematically appraised. An analysis ha ...