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Search results for "Macitentan"

Current therapies for pulmonary arterial hypertension have been adopted on the basis of short-term trials with exercise capacity as the primary end point. The SERAPHIN trial has assessed the efficacy ...


A study has evaluated the effect of Macitentan ( Opsumit ) on hospitalization of patients with symptomatic pulmonary arterial hypertension ( PAH ). PAH is a progressive, life-threatening disease ofte ...


Activation of the endothelin system has been demonstrated in both plasma and lung tissue of PAH ( pulmonary arterial hypertension ) patients. Although it is unclear if the increases in endothelin-1 pl ...