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Search results for "Simvastatin"

The Aggrastat to Zocor study, or A to Z study, phase Z has assessed whether early intensive Simvastatin ( Zocor ) treatment had advantages over a delayed conservative Simvastatin strategy in ACS ( ac ...


Researchers reported at the American Heart Association's Scientific Sessions 2005 that a newly discovered genetic variation, in combination with a second variation, reduces the ability of statin drugs ...


There are conflicting data regarding whether statins predominantly metabolized by CYP3A4 reduce the metabolism of Clopidogrel ( Plavix ) to its active metabolite and diminish its clinical efficacy. ...


The SEAS ( Simvastatin and Ezetimibe in Aortic Stenosis ) study has investigated the effects of intensive cholesterol lowering with the combination of Simvastatin ( 40 dmg daily ) and Ezetimibe ( 10 m ...


Statins, typically prescribed to lower blood cholesterol levels, may also modestly reduce blood pressure. Several previous studies have suggested that statins may have an effect on blood pressure, ...


The FDA ( Food and Drug Administration ) has informed the public that it has revised the dose limitation for the cholesterol-lowering drug Simvastatin from 10 mg to 20 mg when it is co-administered wi ...


A study looking at the data of thousands of patients who suffered myocardial infarctions has suggested treatment with high-potency statins offers a significantly improved chance of survival compared t ...


The purpose of the study was to compare the incidence of new-onset diabetes ( NOD ) with cardiovascular event reduction at different levels of NOD risk. Statins reduce the number of cardiovascular ...


A study has determined all-cause mortality in patients with a first myocardial infarct who were treated with Simvastatin ( Zocor ) compared with high-potency statin and Simvastatin / Ezetimibe ( Vytor ...


A investigational IMPROVE-IT study has met its primary and all secondary composite efficacy endpoints. Treatment with Simvastatin in combination with Ezetimibe ( Vytorin ) has significantly reduced ca ...


IMPROVE-IT ( IMProved Reduction of Outcomes: VYTORIN Efficacy International Trial ), was an international, multi-center, randomised, double-blind active comparator trial of 18,144 high-risk patients p ...


The IMPROVE-IT study met its primary and all secondary composite efficacy endpoints. In IMPROVE-IT, patients taking the LDL-cholesterol-lowering medicine Vytorin ( Ezetimibe / Simvastatin ), which com ...


Recent trials have shown a reduction in the risk of major adverse cardiac events ( MACE ) with Simvastatin and Ezetimibe ( Vytorin ) therapy in patients with acute coronary syndrome. The potential be ...